A high-throughput chemotaxis detection method for CCR4+ T cell migration inhibition using image cytometry

A High Throughput and High Content Analysis of Cell Death Processes Using Microfluidic Image Cytometry (fic)

Microfluidic systems have significant implications in the field of in vitro cell-based assays and drug screening by virtue of their automation and high content screening capabilities. Here, we present our recent efforts to develop a microfluidic platform for high throughput and high content analysis of cell death event. A group of microfluidic devices for monitoring various cell death parameter...

High throughput image cytometry for detection of suspicious lesions in the oral cavity.

The successful management of oral cancer depends upon early detection, which relies heavily on the clinician's ability to discriminate sometimes subtle alterations of the infrequent premalignant lesions from the more common reactive and inflammatory conditions in the oral mucosa. Even among experienced oral specialists this can be challenging, particularly when using new wide field-of-view dire...

High Performance Method for Skin Roughness Detection Using Raman Spectroscopy

Phylogenetic Method for High-Throughput Ortholog Detection

Accurate detection of orthologous proteins is a key aspect of comparative genomics. Orthologs in different species can be used to predict the function of uncontrived genes from model organisms as they retain the same biological function through the path of evolution. Orthologs can be inferred using phylogenetic, pair-wise similarity or synteny based methods. The study here describes a computati...

A quantitative, facile, and high-throughput image-based cell migration method is a robust alternative to the scratch assay.

Cell migration is a key phenotype for a number of therapeutically important biological responses, including angiogenesis. A commonly used method to assess cell migration is the scratch assay, which measures the movement of cells into a wound made by physically scoring a confluent cell monolayer to create an area devoid of cells. Although this method has been adequate for qualitative characteriz...